phoenix is the capital and largest city in the u.s. state of arizona, as well as the fifth most populous city in the united states. phoenix is home to 1,552,259 residents, and is the anchor of the phoenix metropolitan area with 4,179,427 residents. It is currently the largest city in the southwestern region of the u.s. (also known as the "desert southwest") and the mountain west. in addition, phoenix is the county seat of maricopa county, and is one of the largest cities in the united states by land area.

jacksonville is the largest city in the u.s. state of florida and the county seat of duval county. since 1968, as a result of the consolidation of the city and county government (and a corresponding expansion of the city limits to include almost the entire county), jacksonville has been the largest city in land area in the contiguous united states.

chicago is the largest city in the u.s. state of illinois and the midwestern united states, as well as the third-most populous city in the united states. one of the largest cities in north america, chicago is among the world's twenty-five largest urban areas by population, and rated an alpha world city by the world cities study group at loughborough university.

biloxi is a city in harrison county, mississippi, in the united states. along with gulfport, biloxi is a county seat of harrison county. the city is part of the gulfport-biloxi metropolitan area and the gulfport-biloxi-pascagoula, mississippi combined statistical area. the beachfront of biloxi lies directly on the mississippi sound, with barrier islands scattered off the coast and into the gulf of mexico.

rochester is a city in monroe county, new york state, south of lake ontario in the united states. the rochester metropolitan area is the second largest economy in new york state, behind the new york city metropolitan area. Known as the world's image centre, it was also once known as the flour city, and more recently as the flower city. It is the county seat for monroe county.

columbus is the capital, the largest, and the most populous city of the u.s. state of ohio. located near the geographic center of the state, columbus is the county seat of franklin county, although parts of the city also extend into delaware and fairfield counties. named for explorer christopher columbus, the city was founded in 1812 at the confluence of the scioto and olentangy rivers, and assumed the functions of state capital in 1816. the city has a diverse economy based on education (it is home to The ohio state university, the largest university in the united states), insurance, healthcare (three major hospital systems operating in central ohio), retail, and technology. acknowledged by money magazine as the 8th best large city in the u.s. to inhabit, it is also recognized as an emerging global city.

philadelphia is the largest city in pennsylvania and the sixth-most-populous city in the united states. the city is the nation's fourth-largest urban area by population, its fourth-largest consumer media market as ranked by the nielsen media research, and the world's 49th-most-populous city.